Ginger's Potential to Target Cancer Stem Cells: The Power of 6-Shogaol

Devi ShivaShanmi
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The Potential of Ginger in Fighting Cancer: Examining the Research



Cancer is one of the most devastating diseases in the world today. According to the World Health Organization (WHO), cancer is the second leading cause of death globally, with an estimated 10 million deaths in 2020 alone. Cancer is caused by abnormal cell growth and division, which leads to the formation of tumors. There are many different types of cancer, each with its unique characteristics and treatment options.

The Potential of Ginger in Fighting Cancer - The Power of 6-Shogaol in Dried Ginger



One of the biggest challenges of cancer treatment is the high relapse rate. Even when a tumor is removed, cancer can come back because of cancer stem cells. Cancer stem cells are the "mother" of cancer cells and are responsible for the uncontrolled and fast growth of cancer cells. These stem cells can be resistant to chemotherapy and can self-renew, leading to the formation of new tumor colonies. Therefore, finding a way to kill cancer stem cells is essential in preventing cancer recurrence.



Ginger, a common spice used in many cuisines worldwide, has been found to have potential in fighting cancer. In particular, a component of dried ginger called 6-Shogaol has been shown to be effective in targeting cancer stem cells. In this article, we will examine the research on the potential of ginger in fighting cancer, with a focus on breast cancer.


Ginger and Cancer Stem Cells



Ginger is a flowering plant that originated in Southeast Asia and is now grown in many parts of the world. The root of the ginger plant is commonly used as a spice in cooking and as a natural remedy for various ailments. Ginger has been used for centuries in traditional medicine to treat a variety of conditions, including nausea, inflammation, and pain.



In recent years, researchers have begun to investigate the potential of ginger in fighting cancer. One of the reasons why ginger may be effective in fighting cancer is its ability to target cancer stem cells. Cancer stem cells are responsible for the growth and spread of cancer and are often resistant to chemotherapy. Therefore, finding a way to kill cancer stem cells is essential in preventing cancer recurrence.


Dried Ginger vs. Fresh Ginger


Interestingly, dried ginger has been found to be more effective than fresh ginger in targeting cancer stem cells. This is because dried ginger contains a compound called Shogaols, which are dehydration products of ginger that are not present in the fresh root. When ginger is dried, gingerols are converted into Shogaols, which have properties that fresh ginger doesn't. As a result, dried ginger could be more effective against cancer stem cells than fresh ginger.


The Role of 6-Shogaol in Targeting Cancer Stem Cells



In a study published in PLoS One, researchers investigated the effect of 6-Shogaol, a component of dried ginger, on breast cancer stem cells. The researchers found that 6-Shogaol was 10,000 times more effective than chemotherapy in targeting the root cause of breast cancer malignancy, which is cancer stem cells. They also found that 6-Shogaol was able to kill cancer stem cells without adversely affecting healthy tissue. The study suggests that 6-Shogaol may be a promising natural treatment for breast cancer.


The Recommended Dosage



Ginger has been tested on different kinds of cancers, including breast, ovarian, prostate, and colon cancer. Researchers have found that consumption of dried ginger appears to be safe and effective at a dose between 100 milligrams to 2 grams per day. This is the equivalent to half to one teaspoon of dried ginger daily in your food and drink.



When adding ginger to your diet, it is important to discuss any changes you make with your doctor first. It is also important to try and find dried ginger that has not been heated over 85 degrees Fahrenheit

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